This year’s World Brain Day aims to make brain health accessible to “everyone, everywhere,” as many people globally cannot access essential care. The scientific frontier of cognitive health is expanding, leveraging AI to translate large-scale public nutrition research into meaningful dietary approaches to mental well-being. In Europe, new EU funding is giving rise to computer generative modeling to decode complex diet-microbiome signatures across diverse national diets, while ingredient developers are addressing a saturated supplements market through more targeted clinical differentiation.